منابع مشابه
Finding a cure for HIV: will it ever be achievable?
Combination antiretroviral therapy (cART) has led to a major reduction in HIV-related mortality and morbidity. However, HIV still cannot be cured. With the absence of an effective prophylactic or therapeutic vaccine, increasing numbers of infected people, emerging new toxicities secondary to cART and the need for life-long treatment, there is now a real urgency to find a cure for HIV.There are ...
متن کاملWhat Will It Take to Cure HIV?
Investigational strategies to attempt HIV cure or remission include very early initiation of antiretroviral therapy to limit the latent HIV reservoir and preinfection vaccination. In the setting of viral suppression, strategies include reactivation of latently infected cells (eg, through "shock" therapy with histone deacetylase inhibitors or other agents); use of broadly neutralizing antibodies...
متن کاملWill xenotransplantation ever be feasible?
In several recent conferences, the principal questions have been whether xenotransplantation technology should be encouraged and, if so, how it should be regulated. Because the prospect of successful transplantation of animal organs into humans is still remote, the rush to achieve consensus about clinical application would be inexplicable were it not for two ostensibly unrelated issues. The fir...
متن کاملWill LEDGIN molecules be able to play a role in a cure for HIV infection?
Article history: Received 5 May 2016 Accepted 5 May 2016 Available online 7 May 2016 lishment of latency, as the cellular transcriptional state influences both HIV transcription driven by its promoter located in the long terminal region (LTR) and reactivation from latency. Inhibitors that target the interaction between integrase and LEDGF are variously termed noncatalytic integrase inhibitors (...
متن کاملWill this paper ever be cited?
It is an accepted fact of academic life that some papers, in whatever discipline and wherever published, will never be cited. Empirical support for this can be found in studies such as those reported by Glanzel (1992), Rousseau (1994), and Egghe (2000) where the distribution of the time of first citation is investigated. In all cases, it is assumed that never-citation is connected with the perc...
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ژورنال
عنوان ژورنال: Journal of the International AIDS Society
سال: 2011
ISSN: 1758-2652
DOI: 10.1186/1758-2652-14-4